My current academic status is a graduate student in biophysics. I am a weighing my options of either going to industry or academia after graduation. This book has given me a lot of worthwhile suggestions. There are certainly some factors that I haven't even considered until I read this book. The book also taught me a lot of 'survival skills' that I should start practicing.
I believe that a lot of my peers are going through graduate school with ignorance on skills that are not directly related to physics, such as presentation skills, publishing and writing skills, and communication skills. These are probably more important in finding a secure job than a high IQ brain.
One of the main goal of this book is to help us consider the ingredients needed for a secure and stable scientific career. I believe this will save some of us a lot of headaches in the future.
For negatives, I believe that the author tries to assume that we (the audience) are all high caliber students and postdocs. I definitely don't consider myself someone who will make any major contribution to science, or being capable of publishing 1 paper every year or so. I don't know if I can even produce 1 publication within my entire graduate career. Furthermore, I really wish there were more in-depth discussion on finding the right mentor in the academic and industrial world. Despite the cons, I still think this book should be read by all serious researchers.
I didn't give this excellent book five stars because it is such a short book, and short on concrete detail and example. If you're serious about the issues discussed in the book, you'll want to pick up one or more related books out there (which often cite this one positively, by the way). Don't skip this one, though. You can read it in a hour or two every few years as a reminder/checklist about what you should be doing.